Recombinant Cadherin-16 anticorps (AA 350-550)

N° du produit ABIN7863797

Cet anticorps Lapin Monoclonal détecte spécifiquement Cadherin-16 dans IHC et WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant Cadherin-16 anticorps (AA 350-550) (ABIN7863797)

Antigène: Cadherin-16 (CDH16)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin-16 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: CDH16-8800R

Détail du produit anti-Cadherin-16 anticorps

Épitope: AA 350-550

Fonction: Recombinant Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody

Specificité: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. 79oΩKsp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Purification: 200ug/ml of Ab purified by Protein A.

Immunogène: Recombinant fragment (around aa350-550) of human CDH16 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: Ksp-Cadherin

Sujet:

Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody

Normal kidney or renal cell carcinoma.

Poids moléculaire: 130kDa

ID gène: 1014, 513660