Recombinant Cadherin-16 anticorps (AA 350-550)
Aperçu rapide pour Recombinant Cadherin-16 anticorps (AA 350-550) (ABIN7857995)
Antigène
Voir toutes Cadherin-16 (CDH16) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 350-550
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Fonction
- Recombinant Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody
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Specificité
- This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. 79oΩKsp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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Purification
- 200ug/ml of Ab purified by Protein A.
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Immunogène
- Recombinant fragment (around aa350-550) of human CDH16 protein (exact sequence is proprietary)
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Isotype
- IgG, kappa
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Cadherin-16 (CDH16)
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Autre désignation
- Ksp-Cadherin
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Sujet
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Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody
Human kidney or renal cell carcinoma.
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Poids moléculaire
- 130kDa
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ID gène
- 1014, 513660
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UniProt
- O75309
Antigène
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