Recombinant HLA-ABC anticorps (AA 100-300)

N° du produit ABIN7863894

Cet anticorps anti-HLA-ABC Monoclonal Lapin (Clone MHC-I-8147R) (ABIN7863894) détecte spécifiquement HLA-ABC dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant HLA-ABC anticorps (AA 100-300) (ABIN7863894)

Antigène: HLA-ABC

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-ABC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: MHC-I-8147R

Détail du produit anti-HLA-ABC anticorps

Épitope: AA 100-300

Fonction: Recombinant HLA Class 1 ABC (MHC I) Antibody

Specificité: Major Histocompatibility Complex (MHC) is a genetic region on chromosomes composed of tightly linked highly polymorphic gene loci that encode cell surface specific proteins, depending on the structure and function of genes and coding products. We divide MHC into class 79oΩ 79oΩ, class 79oΩ 79oΩ and class 79oΩ 79oΩ gene regions. Endogenous antigen presentation is presented by the major histocompatibility complex 79oΩ 79oΩ (MHC 79oΩ 79oΩ) pathway. Intracytoplasmic proteins are decomposed into peptides during protease degradation, which in turn are delivered by HSP41 and HSP90 proteins to TAP on the membrane. MHC 79oΩ 79oΩ is widely distributed on the surface of almost all nucleated cells, including spleen, lymph nodes and thymus lymphocytes in normal tissues. It is also expressed in skin, lung, kidney, liver and heart tissues. It is also widely expressed in tumor tissues. MHC 79oΩ 79oΩmolecular typing is related to the matching of organ transplantation and bone marrow transplantation, as well as a variety of autoimmune diseases.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa100-300) of human HLA-I protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur HLA-ABC

Antigène: HLA-ABC

Autre désignation: HLA Class 1 ABC

Sujet:

Antigen Presenting Molecule, Cw*1701, D6S204, FLJ27082, HLA A, HLA B, HLA C, HLA class 1 A, HLA class 1 B, HLA class 1 C, HLA JY3, HLAA, HLAB, HLAC, HLC C, Human Leucocyte Antigen C, Major Histocompatibility Complex Class I A, Major Histocompatibility Complex Class I B, Major Histocompatibility Complex Class I C, Major histocompatibility complex, class I, A + B + C, MHC class I antigen A*1, MHC Class I Antigen, MHC class I antigen B*7, MHC class I antigen Cw*1, MHC class I HLA A, MHC class I HLA B, MHC class I HLA C, MHC HLA ABC,

HOP-92, Lung, Hep G2, Human tonsil or lymph node. Human Spleen, Guinea pig Spleen, Human Lung or Guinea pig Lung

Poids moléculaire: 40/41kDa

ID gène: 3105, 3106, 3107

UniProt: P01889, P30443, P30499

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints