Recombinant PD-L1 anticorps (AA 190-290)

N° du produit ABIN7859322

L’anticorps anti-PD-L1 Monoclonal Lapin est utilisé pour la détection de PD-L1 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant PD-L1 anticorps (AA 190-290) (ABIN7859322)

Antigène: PD-L1 (CD274 (PD-L1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-L1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: PDL1-8222R

Détail du produit anti-PD-L1 anticorps

Épitope: AA 190-290

Fonction: Recombinant PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody

Specificité: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa190-290) of human CD274 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PD-L1

Antigène: PD-L1 (CD274 (PD-L1))

Autre désignation: PD-L1

Sujet:

B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1

Human placenta|spleen or tonsil tissue. Kidney, lung, Raji

Poids moléculaire: 37-50kDa

ID gène: 29126, 521989

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints