IL3RA anticorps (AA 26-171)
Aperçu rapide pour IL3RA anticorps (AA 26-171) (ABIN7859670)
Antigène
Voir toutes IL3RA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 26-171
-
Fonction
- IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody
-
Specificité
- CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
-
Purification
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
-
Immunogène
- Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary)
-
Isotype
- IgG2b, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS
-
Agent conservateur
- Azide free
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Date de péremption
- 24 months
-
-
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
-
Autre désignation
- IL3RA
-
Sujet
-
CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal
Lymph Node or Stomach., RPMI-8226 or HDLM-2 cells. Tonsil, THP-1
-
Poids moléculaire
- 70kDa
-
ID gène
- 3563, 632790
-
UniProt
- P26951
-
Pathways
- Signalistation JAK/STAT
Antigène
-