Mesothelin anticorps (AA 273-407)

N° du produit ABIN7859710

Cet anticorps anti-Mesothelin Monoclonal Souris (Clone MSLN-2132) (ABIN7859710) détecte spécifiquement Mesothelin dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Mesothelin anticorps (AA 273-407) (ABIN7859710)

Antigène: Mesothelin (MSLN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Western Blotting (WB)

Clone: MSLN-2132

Détail du produit anti-Mesothelin anticorps

Épitope: AA 273-407

Fonction: Mesothelin (Mesothelial Marker) Antibody

Specificité: Mesothelin is a 40 kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69 kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 273-407) of human Mesothelin (MSLN) protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: Mesothelin

Sujet:

CAK1, Megakaryocyte potentiating factor, Mesothelin, MSLN, SMR, SMRP

OVCAR-3 cells, CAPAN-2 or HeLa cells. Lung Mesothelioma.

Poids moléculaire: 40kDa (Mature form), 69kDa (Precursor)

ID gène: 10232, 408488

UniProt: Q13421

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process