Cadherin-16 anticorps (AA 300-600)

N° du produit ABIN7859853

L’anticorps anti-Cadherin-16 Monoclonal Souris est utilisé pour la détection de Cadherin-16 dans des échantillons de Humain. Il a été validé pour IHC et WB.

Aperçu rapide pour Cadherin-16 anticorps (AA 300-600) (ABIN7859853)

Antigène: Cadherin-16 (CDH16)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin-16 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: CDH16-2449

Détail du produit anti-Cadherin-16 anticorps

Épitope: AA 300-600

Fonction: Ksp-Cadherin / CDH16 (Renal Cell Marker) Antibody

Specificité: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. 79oΩKsp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 300-600) of human CDH16 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: Ksp-Cadherin

Sujet:

Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody

Human kidney or renal cell carcinoma.

Poids moléculaire: 130kDa

ID gène: 1014, 513660