MMP2 anticorps (AA 557-569)

N° du produit ABIN7860396

L’anticorps anti-MMP2 Monoclonal Souris est utilisé pour la détection de MMP2 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour MMP2 anticorps (AA 557-569) (ABIN7860396)

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: 4D3

Détail du produit anti-MMP2 anticorps

Épitope: AA 557-569

Fonction: MMP2 / Collagenase Type IV A (Tumor Metastasis Marker) Antibody

Specificité: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human MMP2 protein fragment (aa557-569)

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: MMP2

Sujet:

72kD type IV collagenase, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, Gelatinase A, Gelatinase alpha, Gelatinase neutrophil, Matrix metalloproteinase-2, MMP2, MONA, Neutrophil gelatinase, PEX, TBE-1

U-138 MG or U-87 MG cells. Human placenta or colon carcinoma.

Poids moléculaire: 72kDa (Pro), 63kDa (cleaved)

ID gène: 4313, 513617

UniProt: P08253

Pathways: Activation of Innate immune Response