Recombinant CD35 anticorps (AA 600-900)

N° du produit ABIN7860462

L’anticorps anti-CD35 Monoclonal Lapin est utilisé pour la détection de CD35 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant CD35 anticorps (AA 600-900) (ABIN7860462)

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD35 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: CR1-8282R

Détail du produit anti-CD35 anticorps

Épitope: AA 600-900

Fonction: Recombinant CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody

Specificité: CD35, complement receptor 1, is a cell membrane-bound, monomeric glycoprotein on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils, and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa600-900) of human CR1 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CD35

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Autre désignation: CD35

Sujet:

C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen

Follicular dendritic cells (FDC) in tonsil.

Poids moléculaire: 224kDa

ID gène: 1378, 334019

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity