PKC anticorps (C-Term)

N° du produit ABIN7860719

Cet anticorps Souris Monoclonal détecte spécifiquement PKC dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PKC anticorps (C-Term) (ABIN7860719)

Antigène: PKC (Protein Kinase C (PKC))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PKC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 133

Détail du produit anti-PKC anticorps

Épitope: C-Term

Fonction: Protein Kinase C α / PRKCA Antibody

Specificité: Protein Kinase C alpha (PKC°™) is involved in the regulation of cell proliferation during cell cycle progression. This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Clone 133 recognizes the °™ isoform of PKC°™ and binds to a sequence at the C terminus of PKC°™ to detect its expression in vitro.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Full-length protein corresponding to PKC alpha. Recognizes sequence PQFVHPILQSAV at the C terminus at PKCα.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PKC

Antigène: PKC (Protein Kinase C (PKC))

Autre désignation: Protein Kinase C α

Sujet:

PKC alpha, PKC-A, PKC-alpha, PKCA, PRKCA, Protein kinase C alpha, Protein kinase C alpha type

Normal human kidney or tonsil tissue. HEK293 whole cell lysates.

Poids moléculaire: 77kDa

ID gène: 5578, 531704, 708867

UniProt: P17252

Pathways: TCR Signaling, Regulation of G-Protein Coupled Receptor Protein Signaling, Interaction of EGFR with phospholipase C-gamma, Phototransduction