Recombinant Growth Hormone 1 anticorps
Aperçu rapide pour Recombinant Growth Hormone 1 anticorps (ABIN7861386)
Antigène
Voir toutes Growth Hormone 1 (GH1) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Recombinant Growth Hormone (Pituitary Marker) Antibody
-
Specificité
- Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
-
Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
Immunogène
- Recombinant full-length human GH1 protein
-
Isotype
- IgG, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS
-
Agent conservateur
- Azide free
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Date de péremption
- 24 months
-
-
- Growth Hormone 1 (GH1)
-
Autre désignation
- Growth Hormone
-
Sujet
-
GH-N, GH1, Growth hormone 1, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin
Pituitary cells. Human pituitary tissue (IHC).
-
Poids moléculaire
- 20kDa
-
ID gène
- 2688, 655229
-
UniProt
- P01241
-
Pathways
- Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
Antigène
-