Recombinant Interferon gamma anticorps
Aperçu rapide pour Recombinant Interferon gamma anticorps (ABIN7862972)
Antigène
Voir toutes Interferon gamma (IFNG) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant Interferon gamma (IFNG) Antibody
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Specificité
- Recognizes a protein of 20-25 kDa, identified as human interferon. This MAb is specific to human IFN-Á, and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-Á. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-°™/ æ (type I interferon).
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Purified recombinant human full-length IFNG protein
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Isotype
- IgG2a, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Interferon gamma (IFNG)
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Autre désignation
- Interferon gamma
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Sujet
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AMCF1, Beta thromboglobulin like protein, CXC chemokine ligand 8 (CXCL8), Emoctakin, Granulocyte chemotactic protein 1 (GCP1), IFG, IFI, IFN Immune, IFN-gamma (IFNG), Interleukin 8, Interferon gamma, LECT, LUCT, Lymphocyte derived neutrophil activating factor, LYNAP, Macrophage Activating Factor (MAF), Monocyte derived neutrophil activating protein (MONAP), Monocyte derived neutrophil chemotactic factor (MDNCF), Neutrophil activating factor (NAF), Neutrophil activating peptide 1 (NAP1), Neutrophil activating protein 1 (NAP1), SCYB8, T cell chemotactic factor, T Cell Interferon
PMA stimulated human peripheral blood mononuclear cells. Renal or testicular carcinoma. A549.
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Poids moléculaire
- 20-25kDa
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ID gène
- 3458, 856
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UniProt
- P01579
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Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
Antigène
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