MBP anticorps

N° du produit ABIN7863117

Cet anticorps Rat Monoclonal détecte spécifiquement MBP dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Boeuf (Vache), Cheval et Poulet.

Aperçu rapide pour MBP anticorps (ABIN7863117)

Antigène: MBP (Myelin Basic Protein (MBP))

Reactivité: Humain, Boeuf (Vache), Cheval, Poulet

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp MBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: MBP-4274

Détail du produit anti-MBP anticorps

Fonction: Myelin Basic Protein Antibody

Specificité: Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30 % of the total protein and about 10 % of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas. MBP/4274 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Reacts with human MBP, recognizing epitopes in the 36-50 amino acid region (GILDSIGRFFGGDRG).

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MBP

Antigène: MBP (Myelin Basic Protein (MBP))

Autre désignation: Myelin Basic Protein

Sujet:

GDB, Golli MBP, myelin basic protein, Hemopoietic MBP, HMBPR, HUGO, MLD, Myelin A1 Protein, basic, Myelin Deficient, Myelin membrane encephalitogenic protein, SHI, Shiverer, SP

Human brain or astrocytoma tissue.

Poids moléculaire: 13-21kDa

ID gène: 4155, 551713

UniProt: P02686