Nidogen anticorps

N° du produit ABIN7861824

L’anticorps anti-Nidogen Monoclonal Rat est utilisé pour la détection de Nidogen dans des échantillons de Souris et Cobaye. Il a été validé pour ELISA.

Aperçu rapide pour Nidogen anticorps (ABIN7861824)

Antigène: Nidogen (NID)

Reactivité: Souris, Cobaye

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Nidogen est non-conjugé

Application: ELISA

Clone: ELM1

Détail du produit anti-Nidogen anticorps

Fonction: Nidogen / Entactin Antibody

Specificité: It reacts with the intact (150 kDa) nidogen as well as its proteolytic fragments of 135 kDa, 110 kDa, 100 kDa, and 80 kDa. This MAb does not cross-react with other basement membrane components or fibronectin. Entactin/Nidogen is a ubiquitous multi-domain basement membrane protein. Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Murine EHS laminin preparation

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Nidogen

Antigène: Nidogen (NID)

Autre désignation: Nidogen

Sujet:

Nid1, Ent, Entactin 1, NID-1, Nidogen-1,

Mouse kidney or eye tissue.

Poids moléculaire: 100|105|110|135|and 80kDa