Nidogen anticorps

N° du produit ABIN7881810

Cet anticorps Rat Monoclonal détecte spécifiquement Nidogen dans ELISA. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour Nidogen anticorps (ABIN7881810)

Antigène: Nidogen (NID)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Nidogen est non-conjugé

Application: ELISA

Clone: ELM1

Détail du produit anti-Nidogen anticorps

Fonction: Nidogen Antibody

Purification: Protein G affinity chromatography

Immunogène: A murine EHS laminin preparation was used as the immunogen for the Nidogen antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the Nidogen antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Nidogen antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Nidogen

Antigène: Nidogen (NID)

Autre désignation: Nidogen

Sujet: Entactin/Nidogen is a ubiquitous multi-domain basement membrane protein. Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation. This MAb does not cross-react with other basement membrane components or fibronectin.

UniProt: P10493