Nidogen anticorps

N° du produit ABIN7881809

Cet anticorps anti-Nidogen Monoclonal Rat (Clone ELM1) (ABIN7881809) détecte spécifiquement Nidogen dans ELISA. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Nidogen anticorps (ABIN7881809)

Antigène: Nidogen (NID)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Nidogen est non-conjugé

Application: ELISA

Classe de qualité: Carrier-free

Clone: ELM1

Détail du produit anti-Nidogen anticorps

Fonction: Nidogen Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A murine EHS laminin preparation was used as the immunogen for the Nidogen antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the Nidogen antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Nidogen antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Nidogen

Antigène: Nidogen (NID)

Autre désignation: Nidogen

Sujet: Entactin/Nidogen is a ubiquitous multi-domain basement membrane protein. Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation. This MAb does not cross-react with other basement membrane components or fibronectin.

UniProt: P10493