beta-2 Microglobulin anticorps
Aperçu rapide pour beta-2 Microglobulin anticorps (ABIN7865565)
Antigène
Voir toutes beta-2 Microglobulin (B2M) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- anti-Beta-2-microglobulin mouse monoclonal, EBS-O-109, purified
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Réactivité croisée (Details)
- not with non human primates
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Purification
- affinity chromatography
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Immunogène
- human PBL from a T-ALL patient
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Isotype
- IgG2a kappa
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Indications d'application
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FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
elisa_dilution: assay dependent
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100 μg/mL
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Buffer
- PBS with 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- store at 2 - 8 °C
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Autre désignation
- Beta-2-microglobulin
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Sujet
- EBS-O-109 reacts with human β-2 microglobulin, a 22 kDa protein, which associates non-covalently with the 44 kDa α1-chain of the HLA Class I complex found on all nucleated cells and on platelets. There is no reaction with erythrocytes, neither with non-human primate cells. The detection of β-2 microglobulin in body fluids has been used as a tumor marker, renal failure marker and for monitoring patients with HIV infection. Positive control: Human PBL.
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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