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beta-2 Microglobulin anticorps (Biotin)

B2M Reactivité: Humain, Porc WB, FACS, ELISA, IHC (p) Hôte: Souris Monoclonal B2M-02 Biotin
N° du produit ABIN93901
  • Antigène Voir toutes beta-2 Microglobulin (B2M) Anticorps
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Reactivité
    • 208
    • 53
    • 31
    • 27
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Porc
    Hôte
    • 118
    • 115
    • 11
    • 9
    • 1
    • 1
    Souris
    Clonalité
    • 138
    • 116
    • 1
    Monoclonal
    Conjugué
    • 114
    • 32
    • 26
    • 16
    • 13
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp beta-2 Microglobulin est conjugé à/à la Biotin
    Application
    • 130
    • 115
    • 73
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    • 32
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    • 2
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    • 2
    • 2
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    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    The mouse monoclonal antibody B2M-02 reacts with beta2-microglobulin (beta2M), an extracellular antigen associated with cell-surface MHC Class I molecules and other membrane antigens, as well as it reacts with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
    Réactivité croisée (Details)
    Human, Porcine
    Purification
    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
    Immunogène
    Purified isolated human beta2-microglobulin.
    Clone
    B2M-02
    Isotype
    IgG1
    Top Product
    Discover our top product B2M Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-2 μg/mL, positive control: PBL cell line, negative control: DAUDI human lymphoma cell line, erythrocytes.
    Commentaires

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Avoid prolonged exposure to light.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Drbal, Angelisová, Hilgert, Cerný, Novák, Horejsí: "A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells." dans: Blood, Vol. 98, Issue 5, pp. 1561-6, (2001) (PubMed).

    Hilgert, Horejsí, Kristofová: "The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin." dans: Folia biologica, Vol. 30, Issue 6, pp. 369-76, (1985) (PubMed).

  • Antigène
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Autre désignation
    beta2-Microglobulin (B2M Produits)
    Synonymes
    anticorps Ly-m11, anticorps beta2-m, anticorps beta2m, anticorps bwm, anticorps wu:fa94c05, anticorps wu:fb10a09, anticorps b2m-W01, anticorps b2m-W03, anticorps b2m-Z01, anticorps b2m-Z02, anticorps b2m-Z03, anticorps B2M, anticorps b2m, anticorps B2MG, anticorps wu:fb66f11, anticorps wu:fj01f08, anticorps zgc:64161, anticorps b-2-m, anticorps beta-2-microglobulin, anticorps beta-2 microglobulin, anticorps beta-2-microglobulin S homeolog, anticorps beta-2-microglobulin, like, anticorps B2M, anticorps B2m, anticorps b2m, anticorps b2m.S, anticorps b2ml
    Sujet
    Beta-2-microglobulin,Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.,B2M
    ID gène
    567
    UniProt
    P61769
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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