CD70 anticorps

N° du produit ABIN7865603

Cet anticorps Souris Monoclonal détecte spécifiquement CD70 dans ELISA, IHC, FACS, IF, IP et ICC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD70 anticorps (ABIN7865603)

Antigène: CD70 (CD70 Molecule (CD70))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD70 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: EBS-CD-039

Détail du produit anti-CD70 anticorps

Fonction: anti-CD70 mouse monoclonal, EBS-CD-039, purified

Purification: affinity chromatography

Immunogène: human WM-1 (Waldenstrom's macroglobulinemia) cells

Isotype: IgG1 kappa

Information d'application

Indications d'application:

ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70

Sujet: CD70 is a 30 kDa cytokine that belongs to the tumor necrosis factor (TNF) ligand family. CD70 is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and b-lymphocytes. It induces proliferation of co-stimulated T-cells, enhaces the generation of cytolytic T-cells, and constributes to T-cell activation. It futher plays a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. EBS-CD-039 blocks the interaction between CD27 and CD70, and has been shown to inhibit T-cell proliferation induced by dendritic cells. Positive control: Raji cells, lymph node or tonsil.

Pathways: Cancer Immune Checkpoints