ITGAL anticorps

N° du produit ABIN7865659

Cet anticorps anti-ITGAL Monoclonal Souris (Clone 87-6F9) (ABIN7865659) détecte spécifiquement ITGAL dans FACS, WB, IHC, IF et ICC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ITGAL anticorps (ABIN7865659)

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGAL est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 87-6F9

Détail du produit anti-ITGAL anticorps

Fonction: anti-CD11a mouse monoclonal, 87-6F9, purified

Purification: affinity chromatography

Immunogène: stimulated human leucocytes

Isotype: IgG2b kappa

Information d'application

Indications d'application:

ICC/IF_dilution: assay dependent

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

WB_dilution: 1:50-1:100 (1-2 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur ITGAL

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Autre désignation: CD11a

Sujet: 87-6F9 Reacts with CD11a, a transmembrane molecule with 1145 amino acid residues and a MW of 180 kDa. CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages. Levels on memory T-cells tend to increase. CD11a plays a key role in mediating leukocyte adhesion to endothelium during inflammatory response through binding to ICAM 1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many other T-cell functions and immune phenomena. When paired with CD18, it forms the integrin alphaLbeta2 adhesion. 87-6F9 potently blocks LFA-1 dependent homotypic cell aggregation and was typed in the IVth International Leucocyte Typing Workshop. Positive control: Human leucocytes.

Pathways: Activated T Cell Proliferation, Integrin Complex