Integrin Alpha2b anticorps

N° du produit ABIN7865660

Cet anticorps Souris Monoclonal détecte spécifiquement Integrin Alpha2b dans FACS, IHC, IF et ICC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Integrin Alpha2b anticorps (ABIN7865660)

Antigène: Integrin Alpha2b (CD41)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin Alpha2b est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 96-2C1

Détail du produit anti-Integrin Alpha2b anticorps

Fonction: anti-CD41a mouse monoclonal, 96-2C1, purified

Purification: affinity chromatography

Immunogène: stimulated human PBL

Isotype: IgG1 kappa

Information d'application

Indications d'application:

ICC/IF_dilution: 1:50-1:100 (1-2 μg/mL)

FACS_dilution: 1-2 μg/million cells

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur Integrin Alpha2b

Antigène: Integrin Alpha2b (CD41)

Autre désignation: CD41a

Sujet: 96-2C1 reacts with a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa, integrin IIa/3), a dimer of 90 and 140 kDa, present on the membrane of normal platelets and megakaryocytes. This complex forms the receptor of fibrinogen, fibronectin and Von Willebrand factor, and mediates platelet adhesion and aggregation. MAbs to CD41a have been shown to have anti-proliferative effects on various lymphoid cell lines, particularly those derived from large cell lymphomas. 96-2C1 was typed at the IIId HLDA workshop. Positive control: KG1a, HEL cells, and human platelets in lymph nodes or tonsils.

Pathways: Integrin Complex