SOX2 anticorps
Aperçu rapide pour SOX2 anticorps (ABIN7865738)
Antigène
Voir toutes SOX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- anti-SOX-2 mouse monoclonal, IHC665, purified
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Purification
- affinity chromatography
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Immunogène
- Recombinant Human SOX-2
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Isotype
- IgG1
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Indications d'application
- Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- store at 2 - 8 °C
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Autre désignation
- SOX-2
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Sujet
- SOX2, also known as SRY (Sex Determining Region Y)-Box 2, is a transcription factor that acts to regulate pluripotency of undifferentiated embryonic stem cells, and to regulate gene expression in the stomach. This diagnostic grade SOX2 IVD antibody is used to detect melanoma, testicular germ cell tumour, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and teratoma of the central nervous system. SOX2 has been reported as a predictor of poor outcome in stage I lung adenocarcinomas. Anti-SOX2 is also used to recognize squamous cell carcinomas of the lung and gastrointestinal tract, and may be useful for detecting embryonal carcinoma.
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Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Antigène
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