Calreticulin anticorps

N° du produit ABIN7867123

Cet anticorps anti-Calreticulin Monoclonal Lapin (Clone 1A8) (ABIN7867123) détecte spécifiquement Calreticulin dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Calreticulin anticorps (ABIN7867123)

Antigène: Calreticulin (CALR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Calreticulin est non-conjugé

Application: ELISA

Clone: 1A8

Détail du produit anti-Calreticulin anticorps

Fonction: Anti-CALR antibody(1A8), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Information d'application

Indications d'application: ELISA 1/5000-10000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Conseil sur la manipulation: Avoid repeated freezing and thawing,After reconstitution, if not intended for use within a month, aliquot and store at -80 °C

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur Calreticulin

Antigène: Calreticulin (CALR)

Autre désignation: CALR

Sujet:

Synonyms: cC1qR,CRT,HEL-S-99n,RO,SSA

Target Background: Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response