Recombinant IL21 Receptor anticorps (PE)

N° du produit ABIN7867339

Cet anticorps anti-IL21 Receptor Chimeric Lapin conjugué à PE (Clone DMC225) (ABIN7867339) détecte spécifiquement IL21 Receptor dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant IL21 Receptor anticorps (PE) (ABIN7867339)

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp IL21 Receptor est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: DMC225

Détail du produit anti-IL21 Receptor anticorps (PE)

Fonction: PE-conjugated Anti-IL21R antibody(DMC225), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C-8°C for 6 months

Date de péremption: 6 months

Détails sur IL21 Receptor

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Autre désignation: IL21R

Sujet:

Synonyms: CD360, IMD56, NILR

Target Background: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

UniProt: Q9HBE5

Pathways: Signalistation JAK/STAT