MICA anticorps (PE)

N° du produit ABIN7867369

Cet anticorps anti-MICA Monoclonal Lapin conjugué à PE (Clone DM157) (ABIN7867369) détecte spécifiquement MICA dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MICA anticorps (PE) (ABIN7867369)

Antigène: MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MICA est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: DM157

Détail du produit anti-MICA anticorps (PE)

Fonction: PE-conjugated Anti-MICA antibody(DM157), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Information d'application

Indications d'application: Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C-8°C for 6 months

Date de péremption: 6 months

Détails sur MICA

Antigène: MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

Autre désignation: MICA

Sujet:

Synonyms: MIC-A, PERB11.1

Target Background: This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]

UniProt: Q29983

Pathways: Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response