Recombinant Melanoma gp100 anticorps (PE)

N° du produit ABIN7867406

Cet anticorps Lapin Chimeric détecte spécifiquement Melanoma gp100 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Melanoma gp100 anticorps (PE) (ABIN7867406)

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp Melanoma gp100 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: DMC420

Détail du produit anti-Melanoma gp100 anticorps (PE)

Fonction: PE-conjugated Anti-PMEL antibody(DMC420), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C-8°C for 6 months

Date de péremption: 6 months

Détails sur Melanoma gp100

Antigène: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Autre désignation: PMEL

Sujet:

Synonyms: D12S53E, gp100, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV

Target Background: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

UniProt: P40967