Angiopoietin 1 anticorps (AA 1-200)

N° du produit ABIN7868368

Cet anticorps anti-Angiopoietin 1 Monoclonal Souris (Clone ANGPT1-3651) (ABIN7868368) détecte spécifiquement Angiopoietin 1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Angiopoietin 1 anticorps (AA 1-200) (ABIN7868368)

Antigène: Angiopoietin 1 (ANGPT1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: ANGPT1-3651

Détail du produit anti-Angiopoietin 1 anticorps

Épitope: AA 1-200

Fonction: Angiopoietin 1 Antibody / ANGPT1 (azide and preservative free)

Purification: Protein G affinity

Immunogène: A portion of amino acids 1-200 from human AGPAT1 protein was used as the immunogen for the Angiopoietin 1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Angiopoietin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Angiopoietin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: Angiopoietin 1

Sujet: This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema.

UniProt: Q15389

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process