RGS18 anticorps (AA 1-230)
Aperçu rapide pour RGS18 anticorps (AA 1-230) (ABIN7868879)
Antigène
Voir toutes RGS18 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-230
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Fonction
- RGS18 Antibody
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Purification
- Affinity purified
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Immunogène
- Recombinant human protein (amino acids M1-D230) was used as the immunogen for the RGS18 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the RGS18 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the RGS18 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
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Autre désignation
- RGS18
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Sujet
- Regulator of G-protein signaling 18 is a protein that in humans is encoded by the RGS18 gene. This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
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UniProt
- Q9NS28
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Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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