CrkL anticorps (AA 1-290)
Aperçu rapide pour CrkL anticorps (AA 1-290) (ABIN7869056)
Antigène
Voir toutes CrkL (CRKL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-290
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Fonction
- Crk-like protein Antibody / CrkL
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Purification
- Antigen affinity purified
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Immunogène
- E. coli-derived recombinant human protein (amino acids M1-H290) was used as the immunogen for the Crk-like protein antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Crk-like protein antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Crk-like protein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
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Autre désignation
- Crk-like protein
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Sujet
- Crk-like protein is a protein that in humans is encoded by the CRKL gene. This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
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UniProt
- P46109
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Pathways
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
Antigène
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