Aurora A anticorps (AA 1-395)
Aperçu rapide pour Aurora A anticorps (AA 1-395) (ABIN7869297)
Antigène
Voir toutes Aurora A (AURKA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-395
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Fonction
- Ark-1 Antibody / Aurora-related kinase 1 / Aurka
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Purification
- Antigen affinity purified
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Immunogène
- Recombinant mouse protein (amino acids M1-S395) was used as the immunogen for the Ark-1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Ark-1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Ark-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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Autre désignation
- Ark-1
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Sujet
- AURKA (Aurora kinase A), also called ARK-1 (Aurora-related kinase 1), AurA, AIK, AURORA2, BTAK, PPP1R47, STK7, STK15, and STK6 is a mitotic centrosomal protein kinase. The main role of AURKA/ARK-1 in tumor development is in controlling chromosome segregation during mitosis. Aurora A / Aurora-related kinase 1 is a member of a family of mitotic serine/threonine kinases. The AURKA gene is overexpressed in many human cancers. Ectopic overexpression in mammalian cells induces centrosome amplification, chromosome instability, and oncogenic transformation, a phenotype characteristic of loss-of-function mutations of p53.
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UniProt
- P97477
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Pathways
- Cycle Cellulaire, Asymmetric Protein Localization
Antigène
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