Recombinant Cyclin E1 anticorps (AA 10-176)

N° du produit ABIN7869687

L’anticorps anti-Cyclin E1 Monoclonal Souris est utilisé pour la détection de Cyclin E1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Recombinant Cyclin E1 anticorps (AA 10-176) (ABIN7869687)

Antigène: Cyclin E1 (CCNE1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin E1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: RCCNE1-4936

Détail du produit anti-Cyclin E1 anticorps

Épitope: AA 10-176

Fonction: Recombinant Cyclin E1 Antibody / CCNE1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 10-176 was used as the immunogen for the Cyclin E1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Cyclin E1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Cyclin E1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Cyclin E1

Antigène: Cyclin E1 (CCNE1)

Autre désignation: Cyclin E1

Sujet: Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases