Cyclin E1 anticorps (AA 10-176)

N° du produit ABIN7869689

Cet anticorps Souris Monoclonal détecte spécifiquement Cyclin E1 dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cyclin E1 anticorps (AA 10-176) (ABIN7869689)

Antigène: Cyclin E1 (CCNE1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin E1 est non-conjugé

Application: ELISA

Classe de qualité: Carrier-free

Clone: CCNE1-2587

Détail du produit anti-Cyclin E1 anticorps

Épitope: AA 10-176

Fonction: Cyclin E1 Antibody / CCNE1 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 10-176) was used as the immunogen for this Cyclin E1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cyclin E1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Cyclin E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Cyclin E1

Antigène: Cyclin E1 (CCNE1)

Autre désignation: Cyclin E1

Sujet: Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

UniProt: P24864

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases