Cyclin E1 anticorps (AA 10-176)

N° du produit ABIN7869690

L’anticorps anti-Cyclin E1 Monoclonal Souris est utilisé pour la détection de Cyclin E1 dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Cyclin E1 anticorps (AA 10-176) (ABIN7869690)

Antigène: Cyclin E1 (CCNE1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin E1 est non-conjugé

Application: ELISA

Clone: CCNE1-2587

Détail du produit anti-Cyclin E1 anticorps

Épitope: AA 10-176

Fonction: Cyclin E1 Antibody / CCNE1

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 10-176) was used as the immunogen for this Cyclin E1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cyclin E1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Cyclin E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Cyclin E1

Antigène: Cyclin E1 (CCNE1)

Autre désignation: Cyclin E1

Sujet: Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

UniProt: P24864

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases