VCP anticorps (AA 10-512)

N° du produit ABIN7869711

L’anticorps anti-VCP Polyclonal Lapin est utilisé pour la détection de VCP dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, ELISA, FACS et IHC (p).

Aperçu rapide pour VCP anticorps (AA 10-512) (ABIN7869711)

Antigène: VCP (Valosin Containing Protein (VCP))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VCP est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-VCP anticorps

Épitope: AA 10-512

Fonction: TER ATPase Antibody / VCP / Valosin-containing protein

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids D10-K512) was used as the immunogen for the TER ATPase antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TER ATPase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TER ATPase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur VCP

Antigène: VCP (Valosin Containing Protein (VCP))

Autre désignation: TER ATPase

Sujet: Valosin-containing protein also called CDC48 is an enzyme that in humans is encoded by the VCP gene. It is a member of the AAA+ (ATPase associated with various activities) protein family. The VCP gene maps to chromosome 9p13.3. It is necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. It is involved in the formation of the transitional endoplasmic reticulum. This gene plays a role in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It also involved in DNA damage response: recruited to double-strand breaks (DSBs) sites in a RNF8- and RNF168-dependent manner and promotes the recruitment of TP53BP1 at DNA damage sites.

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway