PKC iota anticorps (AA 100-300)

N° du produit ABIN7869853

Cet anticorps anti-PKC iota Monoclonal Souris (Clone PRKCI-4912) (ABIN7869853) détecte spécifiquement PKC iota dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PKC iota anticorps (AA 100-300) (ABIN7869853)

Antigène: PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PKC iota est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PRKCI-4912

Détail du produit anti-PKC iota anticorps

Épitope: AA 100-300

Fonction: PKC iota Antibody / PRKCI

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 100-300 was used as the immunogen for the PKC iota antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the PKC iota antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PKC iota antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PKC iota

Antigène: PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))

Autre désignation: PKC iota

Sujet: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (, , , l/i, m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC i 1/2L and are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.

UniProt: P41743

Pathways: Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation