CBS anticorps (AA 102-342)

N° du produit ABIN7869915

L’anticorps anti-CBS Monoclonal Souris est utilisé pour la détection de CBS dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour CBS anticorps (AA 102-342) (ABIN7869915)

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBS est non-conjugé

Application: Western Blotting (WB)

Clone: 7C3B7

Détail du produit anti-CBS anticorps

Épitope: AA 102-342

Fonction: Cystathionine Beta Synthase Antibody / CBS

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids K102-E342) was used as the immunogen for the Cystathionine Beta Synthase antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Cystathionine Beta Synthase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Cystathionine Beta Synthase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CBS

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Autre désignation: Cystathionine Beta Synthase

Sujet: CBS, Cystathionine Beta-Synthase, catalyzes the first irreversible step of transsulfuration. The CBS enzyme is a homotetramer of 63-kD subunits and requires pyridoxal phosphate and heme for activity. The CBS gene, which is mapped to chromosome 21q22, contains 23 exons, ranging in size from 42 to 299 bp. The human CBS protein can substitute for the endogenous yeast CBS protein in Saccharomyces cerevisiae. The catalytic domain of the CBS protein is located in the N-terminal 409 amino acids, and a regulatory domain is located in the C-terminal 142 amino acids.A mutation that deletes the C-terminal 145 amino acids of CBS could restore activity of several CBS mutant alleles found in homocystinurics.

UniProt: P35520