Uroplakin 1B anticorps (AA 109-229)

N° du produit ABIN7870045

Cet anticorps anti-Uroplakin 1B Monoclonal Souris (Clone UPK1B-3273) (ABIN7870045) détecte spécifiquement Uroplakin 1B dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Uroplakin 1B anticorps (AA 109-229) (ABIN7870045)

Antigène: Uroplakin 1B (UPK1B)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Uroplakin 1B est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: UPK1B-3273

Détail du produit anti-Uroplakin 1B anticorps

Épitope: AA 109-229

Fonction: Uroplakin 1B Antibody / UPK1B

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 109-229) was used at the immunogen for this Uroplakin 1B antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Uroplakin 1B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Uroplakin 1B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Uroplakin 1B

Antigène: Uroplakin 1B (UPK1B)

Autre désignation: Uroplakin 1B

Sujet: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.

UniProt: O75841