L’anticorps anti-Uroplakin 1B Monoclonal Lapin est utilisé pour la détection de Uroplakin 1B dans des échantillons de Humain. Il a été validé pour IHC (p).
Recombinant Uroplakin 1B Antibody / UPK1B (azide and preservative free)
Purification
Protein A/G affinity
Immunogène
A recombinant fragment (within amino acids 109-229) of human Uroplakin 1B/UPK1B protein was used as the immunogen for the recombinant Uroplakin 1B antibody.
Optimal dilution of the recombinant Uroplakin 1B antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
-20 °C
Stockage commentaire
Aliquot the recombinant Uroplakin 1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
Uroplakin 1B (UPK1B)
Autre désignation
Uroplakin 1B
Sujet
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.