Recombinant Uroplakin 1B anticorps (AA 109-229)

N° du produit ABIN7870053

L’anticorps anti-Uroplakin 1B Monoclonal Lapin est utilisé pour la détection de Uroplakin 1B dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant Uroplakin 1B anticorps (AA 109-229) (ABIN7870053)

Antigène: Uroplakin 1B (UPK1B)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Uroplakin 1B est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: UPK1B-8976R

Détail du produit anti-Uroplakin 1B anticorps

Épitope: AA 109-229

Fonction: UPK1B Antibody / Uroplakin 1B

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 109-229) from the human protein was used as the immunogen for the UPK1B antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the UPK1B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the UPK1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Uroplakin 1B

Antigène: Uroplakin 1B (UPK1B)

Autre désignation: UPK1B

Sujet: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.

UniProt: O75841