BCL3 anticorps (AA 118-366)
Aperçu rapide pour BCL3 anticorps (AA 118-366) (ABIN7870262)
Antigène
Voir toutes BCL3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 118-366
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Fonction
- B-cell lymphoma 3 Antibody / BCL3
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (amino acids E118-A366) was used as the immunogen for the B-cell lymphoma 3 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the B-cell lymphoma 3 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the B-cell lymphoma 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
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Autre désignation
- B-cell lymphoma 3
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Sujet
- B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
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UniProt
- P20749
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Pathways
- Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus
Antigène
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