Girdin anticorps (AA 1231-1836)

N° du produit ABIN7870361

Cet anticorps Lapin Polyclonal détecte spécifiquement Girdin dans ELISA, WB et FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Girdin anticorps (AA 1231-1836) (ABIN7870361)

Antigène: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Girdin est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-Girdin anticorps

Épitope: AA 1231-1836

Fonction: Girdin Antibody / CCDC88A / GIV

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids K1231-D1836) was used as the immunogen for the Girdin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Girdin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Girdin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Girdin

Antigène: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Autre désignation: Girdin

Sujet: Girdin, also called G alpha-interacting vesicle-associated protein (GIV), is a protein that in humans is encoded by the CCDC88A gene. This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: Q3V6T2