PCDHA6 anticorps (AA 125-801)
Aperçu rapide pour PCDHA6 anticorps (AA 125-801) (ABIN7870383)
Antigène
Voir toutes PCDHA6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 125-801
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Fonction
- PCDHA6 Antibody / Protocadherin alpha-6
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (amino acids D125-Q801) was used as the immunogen for the PCDHA6 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the PCDHA6 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the PCDHA6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PCDHA6 (Protocadherin alpha 6 (PCDHA6))
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Autre désignation
- PCDHA6
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Sujet
- Protocadherin alpha-6 is a protein that in humans is encoded by the PCDHA6 gene. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
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UniProt
- Q9UN73
Antigène
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