F2RL3 anticorps (AA 13-333)

N° du produit ABIN7870469

Cet anticorps Lapin Polyclonal détecte spécifiquement F2RL3 dans WB, ELISA, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour F2RL3 anticorps (AA 13-333) (ABIN7870469)

Antigène: F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F2RL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-F2RL3 anticorps

Épitope: AA 13-333

Fonction: Par4 Antibody / Pawr / Prostate apoptosis response 4 protein

Purification: Affinity purified

Immunogène: A mouse recombinant partial protein (amino acids T13-R333) was used as the immunogen for the Par4 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Par4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Par4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur F2RL3

Antigène: F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

Autre désignation: Par4

Sujet: PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 (Par-4), is a human gene. This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases.

UniProt: Q925B0

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process