Choline Acetyltransferase anticorps (AA 131-704)
Aperçu rapide pour Choline Acetyltransferase anticorps (AA 131-704) (ABIN7870510)
Antigène
Voir toutes Choline Acetyltransferase (CHAT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 131-704
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Fonction
- Choline Acetyltransferase Antibody / ChAT
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Purification
- Antigen affinity purified
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Immunogène
- Recombinant human protein (amino acids L131-S704) was used as the immunogen for the Choline Acetyltransferase antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Choline Acetyltransferase antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Choline Acetyltransferase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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Autre désignation
- Choline Acetyltransferase
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Sujet
- Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
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UniProt
- P28329
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Pathways
- Skeletal Muscle Fiber Development
Antigène
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