MYD88 anticorps (AA 136-164)

N° du produit ABIN7870552

Cet anticorps anti-MYD88 Polyclonal Lapin (ABIN7870552) détecte spécifiquement MYD88 dans WB, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MYD88 anticorps (AA 136-164) (ABIN7870552)

Antigène: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYD88 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MYD88 anticorps

Épitope: AA 136-164

Fonction: MyD88 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MyD88 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MYD88

Antigène: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Autre désignation: MyD88

Sujet: Myeloid differentiation primary response protein MyD88 is an adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.

UniProt: Q99836

Pathways: Signalisation NF-kappaB, Signalisation TLR, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades