Complement Factor H anticorps (AA 136-447)

N° du produit ABIN7870556

Cet anticorps Lapin Polyclonal détecte spécifiquement Complement Factor H dans WB, FACS et IHC (p). Il présente une réactivité avec des échantillons de Rat et Souris.

Aperçu rapide pour Complement Factor H anticorps (AA 136-447) (ABIN7870556)

Antigène: Complement Factor H (CFH)

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement Factor H est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Complement Factor H anticorps

Épitope: AA 136-447

Fonction: Cfh Antibody / Factor H

Purification: Affinity purified

Immunogène: Recombinant mouse protein (amino acids N136-T447) was used as the immunogen for the Cfh antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cfh antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Cfh antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Complement Factor H

Antigène: Complement Factor H (CFH)

Autre désignation: Cfh

Sujet: Factor H is a member of the regulators of complement activation family and is a complement control protein. This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P06909

Pathways: Système du Complément, Cellular Response to Molecule of Bacterial Origin