CLK2 anticorps (AA 140-496)

N° du produit ABIN7870666

Cet anticorps anti-CLK2 Polyclonal Lapin (ABIN7870666) détecte spécifiquement CLK2 dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CLK2 anticorps (AA 140-496) (ABIN7870666)

Antigène: CLK2 (CDC-Like Kinase 2 (CLK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-CLK2 anticorps

Épitope: AA 140-496

Fonction: CLK2 Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids A140-D496) was used as the immunogen for the CLK2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CLK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CLK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CLK2

Antigène: CLK2 (CDC-Like Kinase 2 (CLK2))

Autre désignation: CLK2

Sujet: Dual specificity protein kinase CLK2 is an enzyme that in humans is encoded by the CLK2 gene. It is mapped to 1q22. This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process