MMP14 anticorps (AA 145-174)

N° du produit ABIN7870722

L’anticorps anti-MMP14 Polyclonal Lapin est utilisé pour la détection de MMP14 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC (p) et FACS.

Aperçu rapide pour MMP14 anticorps (AA 145-174) (ABIN7870722)

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-MMP14 anticorps

Épitope: AA 145-174

Fonction: MMP14 Antibody

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 145-174 from the human protein was used as the immunogen for the MMP14 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MMP14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.

UniProt: P50281

Pathways: Autophagy