TIAM1 anticorps (AA 1478-1506)

N° du produit ABIN7870747

Cet anticorps anti-TIAM1 Polyclonal Lapin (ABIN7870747) détecte spécifiquement TIAM1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TIAM1 anticorps (AA 1478-1506) (ABIN7870747)

Antigène: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIAM1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TIAM1 anticorps

Épitope: AA 1478-1506

Fonction: TIAM1 Antibody / T cell lymphoma invasion and metastasis 1

Purification: Antigen affinity

Immunogène: A portion of amino acids 1478-1506 from the human protein was used as the immunogen for the TIAM1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the TIAM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TIAM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur TIAM1

Antigène: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Autre désignation: TIAM1

Sujet: TIAM1 is a protein that plays a crucial role in cell migration and invasion. In T cell lymphoma, increased expression of TIAM1 has been associated with enhanced invasive capabilities of cancer cells. TIAM1 promotes the formation of invasive structures called invadopodia, which facilitate cancer cell movement through tissues. Additionally, TIAM1 has been shown to activate signaling pathways that promote metastasis, making it a key player in the spread of T cell lymphoma. Studies have demonstrated that targeting TIAM1 can inhibit T cell lymphoma invasion. By disrupting the activity of TIAM1, researchers have been able to reduce the ability of cancer cells to invade surrounding tissues. This suggests that TIAM1 could be a potential therapeutic target for inhibiting T cell lymphoma invasion and slowing down disease progression. Metastasis is a major concern in T cell lymphoma, as cancer cells can spread to distant organs and tissues, leading to poor prognosis. TIAM1 has been implicated in promoting the metastatic spread of T cell lymphoma cells. By targeting TIAM1, researchers have observed a decrease in the ability of cancer cells to metastasize, highlighting the potential of TIAM1 as a therapeutic target for preventing T cell lymphoma metastasis.

UniProt: Q13009