NK2 Homeobox 5 anticorps (AA 15-132)

N° du produit ABIN7870781

Cet anticorps Lapin Polyclonal détecte spécifiquement NK2 Homeobox 5 dans WB, ELISA, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NK2 Homeobox 5 anticorps (AA 15-132) (ABIN7870781)

Antigène: NK2 Homeobox 5 (NKX2-5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NK2 Homeobox 5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-NK2 Homeobox 5 anticorps

Épitope: AA 15-132

Fonction: NKX2.5 Antibody

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids K15-R132) was used as the immunogen for the NKX2.5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the NKX2.5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the NKX2.5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur NK2 Homeobox 5

Antigène: NK2 Homeobox 5 (NKX2-5)

Autre désignation: NKX2.5

Sujet: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 directly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development